Feature:

Hydroxypropyl beta-cyclodextrin are purified polydisperse products resulting from the controlled reaction of propylene oxide and native beta-cyclodextrin. Hydroxypropyl beta-cyclodextrin is itself very soluble in water (greater than 500 mg/ml at room temperature compared to 18 mg/ml for beta-cyclodextrin), and is used for molecular encapsulation of a variety of sparingly water compounds to enhance the aqueous solubility of the encapsulated compound.

CAS No.: 128446-35-5

Molecular Formula: C₆₃H₁₁₂O₄₂

Molecular Weight:  1541.54

 Specifications:

1. Appearance: White powder

2. Assay: ≥98%

3. Loss on Drying: ≤4.5%

4. Chloride: ≤0.02%

5. Residue on Ignition: ≤1.5%

6. Heavy Metals: ≤0.0025%

7. As: ≤0.0002%

8. Degree of substitution: 4-9

9. Total bacteria count: ≤1000 pcs/g

10. Moulds and yeasts: ≤100 pcs/g

Application:

Pharmaceutical:

1. Suitable for parenteral use, syrups, solutions and oral suspensions as well as for dry formulations (with possibility of in-situ encapsulation).

2. To increase water solubility of poorly soluble drugs.

3. To increase bioavailability.

4. To improve organoleptic properties of bitter or unpleasant actives.

Cosmetics:

1. Suitable for encapsulation of volatile compounds.

2. To increase shelf life of expensive flavours.